Publication list in Pubmed (Link)
Involvement of the upper respiratory tract and paranasal sinuses in cystic fibrosis (selection)
- Mainz JG, Schumacher U, Schädlich K, Hentschel J, Koitschev C, Koitschev A, Riethmüller J, Prenzel F, Sommerburg O, Wiedemann B, Staab D, Gleiber W, Fischer R, Beck JF, Arnold C; Cooperators. Sino nasal inhalation of isotonic versus hypertonic saline (6.0%) in CF patients with chronic rhinosinusitis – Results of a multicenter, prospective, randomized, double-blind, controlled trial.J Cyst Fibros. 2016 Nov;15(6):e57-e66. doi: 10.1016/j.jcf.2016.05.003. Epub 2016 Jun 5.
- Bock J, Schien M, Gerber A, Naehrlich L, Kaeding M, Guntinas-Lichius O, Arnold, C, Mainz JG Do sinonasal symptoms reported by cystic fibrosis patients correlate to anterior rhinomanometric and rhinoscopic findings? Pediatr Pulmonol. 2017 Feb;52(2):167-174
- Mainz JG, Schädlich K, Schien C, Schelhorn-Neise P, Koitschev A, Keller P, Riethmüller J, Wiedemann B, Beck JF – Sinonasal inhalation of Tobramycin in CF-patients with P.aeruginosa-colonization of the upper airways – results of a multicentric placebo controlled pilot study Drug Design, Development and Therapy 2014:8 209–217
- Hentschel J, Müller U, Doht F, Fischer N, Böer K, Sonnemann J, Hipler U-C, Hünniger K, Kurzai O, Markert UR, Mainz JG – Influences of nasal lavage collection-, processing- and storage methods on inflammatory markers – Evaluation of a method for non-invasive sampling of epithelial lining fluid in cystic fibrosis and other respiratory diseases. Journal of Immunological Methods 12/2013; DOI:10.1016/j.jim.2013.12.003 (in press)
- Michl RK, Fischer C, Beck JF, Mainz JG -Reduced Nasal Nitric Oxide in Cystic Fibrosis Patients with Elevated Systemic Inflammation Markers PLoS One. 2013 Nov 13;8(11):e79141. doi: 10.1371/journal.pone.0079141. PMID:24236100
- Beiersdorf N, Schien M, Hentschel J, Pfister W, Markert U and Mainz JG – Soluble Inflammation Markers in Nasal Lavage from CF-Patients and Healthy Controls, J Cyst Fibros. 2012 Sep 15. doi:pii: S1569-1993(12)00154-3. 10.1016/j.jcf.2012.08.015. [Epub ahead of print]
- Lindig J, Steger C, Beiersdorf N, Michl R, Beck JF, Hummel T, and Mainz JG – Smell in Cystic Fibrosis, Curr Allergy Asthma Rep. 2012 Apr;12(2):163-74. doi: 10,1007/s11882-012-0250-y.
- Mainz JG, Hentschel J, Schien C, Cramer N, Pfister W, Beck JF, Bottlenose dolphin B. – Sinonasal persistence of Pseudomonas aeruginosa after lung transplantation., J Cyst Fibros. 2012 Mar;11(2):158-61. doi: 10.1016/j.jcf.2011.10.009. Epub 2011 Nov 30.
- Mainz JG, Michl R, Pfister W, Beck JF. – Cystic fibrosis upper airways primary colonization with Pseudomonas aeruginosa: eradicated by sinonasal antibiotic inhalation. Am J Respir Crit Care Med. 2011 Nov 1;184(9):1089-90.
- Mainz JG, Schiller I, Ritschel C, Mentzel H-J, Riethmüller J, Koitschev A, Schneider G, Beck JF, Wiedemann B – Sinonasal inhalation of dornase alfa in CF:a double-blind placebo-controlled cross-over pilot trial. Auris Nasus Larynx. 2011 Apr;38(2):220-7. Epub 2010 Oct 27
- Mainz JG, Naehrlich L, Schien M, Käding M, Schiller I, Mayr S, Schneider G, Wiedemann B, Wiehlmann L, Cramer N, Pfister W, Kahl BC, Beck JF, Tümmler B – Concordant genotype of upper and lower airways P. aeruginosa and S. aureus isolates in cystic fibrosis, Thorax 2009;64(6):535-40. Epub 2009 Mar 11.
- MainzJG, Koitschev A – Management of chronic rhinosinusitis in CF, Journal of Cystic Fibrosis 2009; 8 S1: 10-14
Activators and Potentiators of Chloride Channels in CF
- Graeber SY, Hug MJ, Sommerburg O, Hirtz S, Hentschel J, Heinzmann A, Dopfer C, Schulz A, Mainz JG, Tümmler B, Mall MA. Intestinal Current Measurements Detect Activation of Mutant CFTR in Patients with Cystic Fibrosis with the G551D Mutation Treated with Ivacaftor. Am J Respir Crit Care Med. 2015 Nov 15;192(10):1252-5. doi: 10.1164/rccm.201507-1271LE.
- Hebestreit H, Sauer-Heilborn S, Fischer R, Käding M, Mainz JG – Effects of Ivacaftor on cystic fibrosis with at least one G551D mutation and poor pulmonary function J Cyst Fibros. 12 (2013) 599–603 pii: S1569-1993(13)00082-9. doi: 10.1016/j.jcf.2013.05.006.
- Davies JC, Wainwright CE, Canny GJ, Chilvers MA, Howenstine MS, Munck A, Mainz JG, Rodriguez S, Li H, Yen K, Ordoñez C, Ahrens R; on behalf of the VX08-770-103 (ENVISION) Study Group. Efficacy and Safety of Ivacaftor in Patients Aged 6 to 11 Years with Cystic Fibrosis with a G551D Mutation. Am J Respir Crit Care Med. 2013 Jun 1;187(11):1219-25. doi: 10.1164/rccm.201301-0153OC
Abdominal complaints in cystic fibrosis
- Tabori H, Arnold C, Jaudszus A, Mentzel HJ, Renz DM, Reinsch S, Lorenz M, Michl R, Gerber A, Lehmann T, Mainz JG.Abdominal symptoms in cystic fibrosis and their relation to genotype, history, clinical and laboratory findings. PLoS One. 2017 May 4;12(5):e0174463. doi: 10.1371/journal.pone.0174463. eCollection 2017.
Sonographic bone evaluation in asthma
- MainzJG, Kaiser WA, Beck JF, Mentzel H-J – Substantially reduced calcaneal bone ultrasound parameters in severe untreated asthma. Respiration 2009; 78(2):230-3. Epub 2009 Feb 21
- Mainz JG, Sauner D, Malich A, John S, Beyermann H, Mentzel H-J, Kaiser WA, Zintl F – Cross-sectional study on bone density related sonographic parameters in children with asthma – correlation to therapy with inhaled corticosteroids and disease severity. J Bone Miner Metab 2008;26(5):485-92. Epub 2008 Aug 30.
aria
- Michl RK, Tabori H, Hentschel J, Beck JF, Mainz JG. Clinical approach to the diagnosis and treatment of cystic fibrosis and CFTR-related disorders. Expert Rev Respir Med. 2016 Oct 12:1-10. [Epub ahead of print]
- Narayanan S, Mainz JG, Gala S, Tabori H, Grossoehme D. Adherence to therapies in cystic fibrosis: a targeted literature review. Expert Rev Respir Med. 2017 Feb;11(2):129-145. doi: 10.1080/17476348.2017.1280399. Epub 2017 Jan 20.
- Hentschel J, Riesener G, Nelle H, Stuhrmann M, Schöner A, Sommerburg O, Fritzsching E, Mall MA, von Eggeling F, Mainz JG – Homozygous CFTR Mutation M348K in A Boy With Respiratory Symptoms and Failure to Thrive. Disease-Causing Mutation or Benign Alteration?, Eur J Pediatr. 2012 Jul;171(7):1039-46. doi: 10.1007/s00431-012-1672-1. Epub 2012 Jan 25.
- Gerber A, Franz C, Mainz JG – Coincident Diagnosis of a Pulmonary Abscess and Ascaris lumbricoides Infection: a Possible Causal Connection? Klin Padiatr. 2012 Nov;224(7):469-470. Epub 2012 Jul 20.
- Ringer S, Hipler UC, Elsner P, Zintl F and Mainz J – Potential role of the cellular allergen stimulation test (CAST) in diagnosis of allergic bronchopulmonary aspgergillosis (ABPA) in cystic fibrosis. Pediatr Pulmonol 2007;42(4):314-318. PMID: 17335008
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