Korvitol

Korvitol – means to regulate blood pressure.

Pharmacological effects

Korvitol refers to a group of beta1-adrenergic receptor blockers containing metoprolol tartrate.

Korvitolu no peculiarity sympathomimetic activity, it has a membrane stabilizing effect. Application Korvitol reduces the force of the heart rate, the transmission rate of the impulses on the AV node. Metoprolol also reduces renin activity, slightly increasing smooth muscle tension.

Korvitol after internal use is well absorbed in the gastrointestinal tract, the bioavailability is 50%.

The maximum concentration of the active ingredient by the means of reaching 1 5-2ch after ingestion.

product form

The product is made in the form of tablets.

Notes Korvitola

Corvitol indicated according to the instructions for the treatment of cardiovascular diseases: high blood pressure, ischemic heart disease (including prevention reinfarction, treatment of acute myocardial infarction), arrhythmias.

Effective use Korvitola warns of migraine drugs.

Contraindications

Corvitol instructions contraindicated in lactase deficiency, glucose-galactose malabsorption syndrome, hypersensitivity, hypotension, bradycardia, progressive heart failure, shock.

Do not use a tool for patients with AV blockade, sinus 2-3 degrees, the weak sinus syndrome.

It is also contraindicated in patients with corvitol bronchospasm, metabolic acidosis, severe pathology of peripheral circulation.

You cannot simultaneously assign Korvitol with monoamine oxidase inhibitors (MAOIs, except group B), for children up to 16 liters., Patients with severe liver disease.

Caution with the use of Korvitol in elderly patients on a strict diet, diabetes mellitus, with 1st degree AV blockade, myasthenia gravis, pheochromocytoma, stenokadiey Prinzmetala, depression, severe renal insufficiency, liver dysfunction, psoriasis, severe reactions of intolerance in the past.

When using Korvitol, you should exercise particular care when you drive a vehicle, managing other dangerous machinery.

Before surgery, patients receiving Corvitol should alert the anesthetist.

Instructions for use Korvitola

Take Korvitol only orally, after eating you cannot crush the tablet (only cut it into pieces if necessary), swallow it whole.

According to the instructions Korvitol hypertension and angina drink one or two p / day or 50 mg for one p / day – 100 mg. The daily dose is increased in some cases to 200 mg, made in two steps. When you receive this dose in Korvitol keep blood pressure under control.

If arrhythmia drink at 100mg Korvitol one, two p / day.

Acute prescribed 5 mg intravenous metoprolol. If portability is normal, metroprolola administered every two minutes at the same dose, reducing its total to 15 mg (not more than 5 mg per administration). After 15min, if the negative reactions to the drug fail, a single dose of 50 mg of Korvitol is administered orally. After two days of taking 50 mg of the drug every 6 hours. If an intravenous injection is less than 15 mg, the first oral dose should be 25 mg.

When emergency treatment is complete, Korvitol take two 100 mg p / day. Is the treatment of acute heart attack in the hospital, constantly checking the pressure level and EKG.

To prevent migraines, taking 100 mg means one or two p / day.

Permissible daily dose – 400 mg.

Adjust the dose required in the elderly and renal failure patients, and in patients with hepatic impairment the dose of metoprolol is corrected. If there is a need for treatment discontinuation, a gradual reduction in dosage – to prevent the development of withdrawal symptoms.

side effects

Application Korvitol can cause orthostatic hypotension and arterial, arrhythmia, heart failure symptoms, false angina, edema, AV conduction disease, Raynaud syndrome.

Patients with severe peripheral circulatory disorders can develop gangrene.

Even after corvitol, leukopenia, rhinitis, thrombocytopenia, dyspnea, bronchospasm, headache, dizziness, emotional lability, paraesthesia can develop.

Because drug therapy can interfere with sleep, concentration can cause depression, confusion, hallucinations, nightmares, nausea, stomach pain, vomiting, dry mucous membranes, stool disorders. It can also affect sight and hearing, experience tinnitus, conjunctivitis, dry eye mucosal allergies.

In rare cases, after corvitol, hepatitis, cramps, muscle pain, arthritis, development or worsening of diabetes mellitus, joint pain, weight gain, changes in libido, deterioration in effectiveness have been recorded.

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Korvitol – instructions for use, indications, dosage